Anabolic Agents as New Treatment Strategy in Osteoporosis
نویسندگان
چکیده
Osteoporosis is a systemic skeletal disease characterized by low bone mineral density (BMD), microarchitectural deterioration of bone tissue, and an increase in fracture risk [1]. Several drugs have been developed to treat osteoporosis: most of these are inhibitors of bone resorption. Effective treatment of osteoporosis requires not only resorption inhibitors, but al‐ so stimulators of bone formation especially in patients who already have lost a significant degree of bone. Although therapeutic alternatives are available for inhibiting bone resorp‐ tion, options of bone anabolic agents are much more limited with regard to the bone resorp‐ tion inhibitors.
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